Weight Gain With Insulin Pump Therapy

A couple of days ago, a young diabetic Twitter friend from Baghdad asked me if insulin can make you fat.  The quick answer is yes, absolutely.  I thought that would make a good blog article, so here goes.

I don’t remember exactly when I started my insulin pump therapy, but I think it was 6 or 7 years ago.  When I started asking around about it before getting my first pump, everybody told me that I should expect to gain about 20lbs.  I said “WHAT?!!!”  There was no way I was going to get a pump if that was a side effect.  Well, when I checked into it, many people do gain weight, but it’s because using a pump is so much easier than shots, that people just start gorging their pie holes with carbs like they’re no longer diabetic.  More carbs + more insulin = more fat.  I was working out like a bodybuilder at the time, in the gym 4 days a week, lifting seriously, and I knew I could avoid this pitfall.  So I went ahead and got my pump, . . . and never gained a pound.

You see insulin is an anabolic hormone.  That’s a fancy scientific word that means it’s a growth hormone.  When you eat carbs, first they are turned to glucose for transport in the bloodstream, and then they are stored in your muscle cells and liver as glycogen.  When the muscle cells and liver are full, the rest of the glucose is stored as fat.  Insulin is the key to this process.  Without insulin, muscles won’t grow, and neither will fat cells.  So if you’re body can only store 20 carbs per meal (just as an example) in muscle and liver, but you’re eating 60 carbs per meal, and you’re bolusing for 60, then 40 carbs per meal will be stored as fat.  That ratio of what you store in muscle vs. what you store as fat, is different for everyone.  So I’m afraid I can’t give you a magic formula to help you lose weight.  What I can tell you, is that when you start insulin pump therapy, don’t go crazy eating whatever you want just because you don’t have to take shots anymore, and you should do fine.

If you’ve recently become diabetic, and you’re not on a pump yet, like my friend from Baghdad, a different scenario applies.  You see, if you’ve recently been diagnosed as type 1 diabetic, then you’ve not had the right amounts of insulin for a while.  This means limited muscle growth, and limited fat storage.  This is what causes the symptom of sudden, un-explainable, and rapid weight loss before you’re diagnosis, which is a telltale marker of un-diagnosed type 1 diabetes.  So now you get diagnosed, you start taking insulin, and now your body has what it needs to store the glycogen and fat properly.  So you start to gain weight again.

The key for everyone, diabetic or not, is that to control your weight, you have to control your insulin.  To control your insulin, you have to control your carbs.  Low fat diets won’t make you lose weight, and they won’t reduce your cholesterol.  A lower carb diet will (not necessarily low carb, just less carbs), and there’s science to explain why it will.  It’s not calories in, calories out, like so many trainers, doctors, nurses, and dieticians will tell you.  Insulin control is the key to weight loss.  For an amazing book that can teach you about insulin, that’s disguised as a simple diet book, read “Protien Power“.

********** Now ya know, and knowing is half the battle.  Go Joe!!! **********

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Type 1 Diabetic: Insulin vs. Glucagon

So I’ve been studying the role of glucagon in metabolism.  I’ve never really known anything about glucagon, except that when I was a juvenile diabetic, I’d have seizures from low blood sugar, and when I saw my parents coming at me with that weird syringe, I knew it was glucagon.  They never understood that I was totally conscious during my seizures.  So anyway, I always thought glucagon was a form of ultra pure glucose or something, until I read Robb Wolf’s book “The Paleo Solution” back in March of this year.  He barely touched on glucagon, but did mention that it was a hormone, so I knew it wasn’t a form of sugar.

Well now I understand a great deal more about glucagon.  Been studying like a madman.  I understand that it’s insulin’s sister hormone, that they both come from Islets of Langerhans in the pancreas.  Glucagon comes from alpha cells, and insulin from beta cells.  That together, they are the core of metabolism.  A perfect feedback system that regulates energy in your body.  Glucagon is the yin, to insulin’s yang.  Glucagon releases fat to be burned, where insulin stores it for energy later.  Glucagon raises low blood sugar by signalling the liver to convert stored glycogen into glucose via glyconeogenesis.  When blood sugar rises to high, insulin is secreted to store that glucose as glycogen in muscle tissue, or as fat.  When there’s insulin, you can’t burn fat.  When there’s glycogen, you can’t store fat.  Insulin is secreted when you eat carbohydrates.  Glycogen is secreted when you eat protein.

Ok, so I have the basic understanding I think?  Now, as a T1D how does glucagon work inside me, since it doesn’t work at all inside me?  I can’t find these answers yet?  I’m dying to figure this out.  I know how insulin works in a T1D.  I just take it externally.  T1D’s don’t take glucagon externally except in emergencies though, to raise blood sugar quickly.  In a T1D, those Islets of Langerhans are broken, so neither insulin nor glucagon is secreted.  When a T1D’s blood sugar falls, glucagon doesn’t bring us back up like it does in a normal person.  Haven’t you ever seen a diabetic that’s hypoglycemic?  We don’t know our own name or where we are sometimes!  So if our bodies don’t secrete glucagon, how do we burn fat?  I know we as T1D’s need to take external glucose to raise blood sugar.  Does epinepherine work in a T1D for releasing fat to be burned?  If I understand epinepherine (it’s totally possible that I don’t understand anything about all this), it can function similarly to glucagon in the release of fat for energy.  I know that T1D’s can burn fat, because I’ve done it,  but how if glucagon doesn’t work?

If anyone reading this, can explain how a T1D burns fat for energy without a working glucagon system, I would be eternally grateful.  I know I’m trying to understand something  that’s probably a whole course of material, but I’d really like to understand this.  I’m such a health nerd.

Thanks for any help you can offer.

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